Terminalia Chebula
Terminalia Chebula Fruit Extract: Becoming a Star in The Cosmetic Industry for being recognized as a power packed antioxidant with 5 additional anti-aging benefits to slow down aging process. This Natural Ayurvedic Ingredient That Provides Long-Lasting Antioxidant Protection and Reverses Visible Signs of Pollution-Induced Skin Damage. Found to increase Moisture Retention, Counteract Photodamage, Reverses Loss of Collagen, Reduces appearance of Lines & Wrinkles.
A quest to identify plant extracts backed by ancient wisdom as sources of natural antioxidants with long-lasting performance is of high interest since research uncovered that environmental aggressors mediate a pivotal role in skin aging processes by inducing excess levels of reactive oxygen species (ROS) and by inciting inflammation.1,2 Of the many environmental aggressors cited, two of the most influential factors are UV radiation and particulate matter (PM) pollution. Excess formation of ROS causes oxidative stress wherein the buildup of ROS is free to oxidize major biomolecules (proteins, DNA, lipids) and organelles (mitochondria), influence gene expression patterns, alter cellular signaling and impair skin’s barrier function. In addition, based on their size, PM pollution can penetrate into the stratum corneum (SC) and into the deeper dermis to unleash an inflammatory cascade that increases the production of pro-inflammatory cytokines, including interleukin-6 and interleukin-8.3,4 This makes IL-6 and IL-8 important biomarkers for researchers trying to determine whether topical interventions can minimize the deleterious effects of inflammatory stress caused by PM pollution. While regular use of broad-spectrum sunscreens can help combat the deleterious effects of UV radiation exposure, research indicates that comprehensive protection against exposure to the UV radiation and PM pollution requires more holistic strategies to defend against (1) oxidative stress (2) inflammatory stress and (3) skin barrier disruption with concomitant reduction in hydration.5–7
REFERENCE: Clin Cosmet Investig Dermatol. 2021; 14: 1257–1269.
Published online 2021 Sep 17. doi: 10.2147/CCID.S326492
PMCID: PMC8456126
PMID: 34557011